According to our computer model, the Buffalo Bills will beat the Las Vegas Raiders when they meet at Highmark Stadium on Sunday, September 17 (at 1:00 PM ET). We have a complete breakdown, regarding the point spread, total and final score, available below.

The Bills owned the sixth-ranked defense last year (319.1 yards allowed per game), and they were better offensively, ranking second-best with 397.6 yards per game. The Raiders owned the 12th-ranked offense last year (352.5 yards per game), and they were less effective on defense, ranking fifth-worst with 365.6 yards allowed per game.

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Raiders vs. Bills Predictions and Picks

ATS Over/Under Score Prediction
Bills (-7.5) Under (46.5) Bills 23, Raiders 13

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Raiders Betting Info

  • Sportsbooks have implied with the moneyline set for this matchup that the Raiders have a 25.6% chance to win.
  • Las Vegas went 8-9-0 ATS last year.
  • The Raiders covered the spread once when an underdog by 7.5 points or more last season (in two opportunities).
  • Last year, nine Las Vegas games hit the over.
  • Games involving the Raiders last year averaged 46.4 points per game, a 0.1-point differential when compared to the over/under for this contest.

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Bills Betting Info

  • The Bills have a 78.9% chance to win this game based on the moneyline's implied probability.
  • Buffalo went 7-8-0 ATS last season.
  • The Bills were favored by 7.5 points or more 10 times last season, and covered the spread in five of those matchups.
  • Last season, the combined scoring went over the point total six times in Buffalo games.
  • The point total average for Bills games last season was 47.7, 1.2 points higher than the over/under for this matchup.

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Raiders vs. Bills 2022 Scoring Insights

Pts Pts Allowed Home Pts Home Pts Allowed Away Pts Away Pts Allowed
Buffalo 28.4 17.9 31.8 18.4 25.1 17.4
Las Vegas 23.2 24.6 27.1 26.1 19.8 23.2

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