AIDS vaccine created at OHSU may clear virus from body - Hawaii News Now - KGMB and KHNL

AIDS vaccine created at OHSU may clear virus from body

PORTLAND, OR (KPTV) -

An HIV vaccine created by researchers at Oregon Health & Science University may be able to completely wipe out the AIDS-causing virus from the body, the university announced Wednesday.

The vaccine, under development at OHSU's Vaccine and Gene Therapy Institute, is being tested by using a primate form of HIV, called SIV, which causes AIDS in monkeys.

Researchers hope an HIV-form of the vaccine candidate will soon be able to be tested in humans.

The journal Nature published the research results online Wednesday.

Dr. Louis Picker, the lab's associate director, said HIV infection has only been cured in "a very small number of highly-publicized but unusual clinical cases."

In those cases, people with HIV were treated with anti-viral medicines very early after the onset of infection or they received a stem cell transplant to combat cancer.

"This latest research suggests that certain immune responses elicited by a new vaccine may also have the ability to completely remove HIV from the body," Picker said.

The approach uses cytomegalovirus, or CMV, which is a common virus that doctors said is carried by a large percentage of the population. Pairing it with SIV had a unique effect, researchers found, and SIV-infected cells were sought out and destroyed.

Researchers said they were able to teach the monkey's body to better prepare its defenses to combat SIV, and they're hoping their modified CMV will have a similar result in humans.

"What we've shown is that not only does this vaccine control the infection, but it actually eliminates the virus from the body of the monkey," Picker said.

Grants from several organizations, including the Bill and Melinda Gates Foundation, are funding OHSU's research.

Copyright 2013 KPTV-KPDX Broadcasting Corporation. All rights reserved.

  • Hawaii News Now headlinesNewsMore>>

  • In new setback, Uber to lose license to work in London

    In new setback, Uber to lose license to work in London

    Friday, September 22 2017 6:25 AM EDT2017-09-22 10:25:36 GMT
    Friday, September 22 2017 6:36 PM EDT2017-09-22 22:36:54 GMT

    London's transport authority says it won't renew Uber's license to operate in the British capital, arguing that it demonstrates a lack of corporate responsibility with implications in public safety and security.

    More >>

    London's transport authority says it won't renew Uber's license to operate in the British capital, arguing that it demonstrates a lack of corporate responsibility with implications in public safety and security.

    More >>
  • The Latest: Sanders praises McCain's for using 'conscience'

    The Latest: Sanders praises McCain's for using 'conscience'

    Friday, September 22 2017 11:36 AM EDT2017-09-22 15:36:38 GMT
    Friday, September 22 2017 6:36 PM EDT2017-09-22 22:36:48 GMT
    Sen. Rand Paul says despite President Donald Trump's attacks on him for opposing the new GOP health care bill, the measure is a "fake" and he won't support it.More >>
    Sen. Rand Paul says despite President Donald Trump's attacks on him for opposing the new GOP health care bill, the measure is a "fake" and he won't support it.More >>
  • US beefs up NKorea sanctions, Kim Jong Un insults Trump,

    US beefs up NKorea sanctions, Kim Jong Un insults Trump,

    Thursday, September 21 2017 10:25 AM EDT2017-09-21 14:25:57 GMT
    Friday, September 22 2017 6:36 PM EDT2017-09-22 22:36:40 GMT
    (AP Photo/Evan Vucci). President Donald Trump speaks at a meeting with Afghan President Ashraf Ghani at the Palace Hotel during the United Nations General Assembly, Thursday, Sept. 21, 2017, in New York.(AP Photo/Evan Vucci). President Donald Trump speaks at a meeting with Afghan President Ashraf Ghani at the Palace Hotel during the United Nations General Assembly, Thursday, Sept. 21, 2017, in New York.

    President Donald Trump says the U.S. will impose additional sanctions on North Korea over the communist country's nuclear weapons buildup.

    More >>

    President Donald Trump says the U.S. will impose additional sanctions on North Korea over the communist country's nuclear weapons buildup.

    More >>
Powered by Frankly